Achieving glycemic control with intensive insulin therapy in the ICU

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Intensive insulin therapy in the medical ICU.

BACKGROUND Intensive insulin therapy reduces morbidity and mortality in patients in surgical intensive care units (ICUs), but its role in patients in medical ICUs is unknown. METHODS In a prospective, randomized, controlled study of adult patients admitted to our medical ICU, we studied patients who were considered to need intensive care for at least three days. On admission, patients were ra...

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Insulin Therapy for Intensive Glycemic Control in Hospital Patients

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Outcome benefit of intensive insulin therapy in the critically ill: Insulin dose versus glycemic control.

OBJECTIVES Maintenance of normoglycemia with insulin reduces mortality and morbidity of critically ill patients. Here we report the factors determining insulin requirements and the impact of insulin dose vs. blood glucose control on the observed outcome benefits. DESIGN A prospective, randomized, controlled trial. SETTING A 56-bed predominantly surgical intensive care unit in a tertiary tea...

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Glycemic Control in the ICU

From the Departments of Critical Care Medicine and Anesthesia, Hospital for Sick Children, University of Toronto, Toronto (B.P.K.); and Harvard Medical School, Harvard Vanguard Medical Associates, and Beth Israel Deaconess Medical Center — all in Boston (K.C.M.). Address reprint requests to Dr. Kavanagh at the Department of Critical Care Medicine, Hospital for Sick Children, University of Toron...

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Intensive insulin therapy in the medical ICU – not so sweet?

Intervention: On admission, patients were randomly assigned to strict normalization of blood glucose levels (80 to 110 mg per deciliter [4.4 to 6.1 mmol per liter]) with the use of insulin infusion or to conventional therapy (insulin administered when the blood glucose level exceeded 215 mg per deciliter [12 mmol per liter], with the infusion tapered when the level fell below 180 mg per decilit...

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ژورنال

عنوان ژورنال: Critical Care

سال: 2008

ISSN: 1364-8535

DOI: 10.1186/cc6380